Publications

2024

  • Lorenzo-Orts, L.#, Strobl, M., Steinmetz, B., Leesch, F., Pribitzer, C., Roehsner, J., Schutzbier, M., Duernberger, G., Pauli, A.# (2024). eIF4E1b is a non-canonical eIF4E protecting maternal dormant mRNAs. EMBO Rep. Jan;25(1):404-427 Epub 2023 Dec 14 (bioRxiv: 10.1101/2023.06.10.544440). doi:10.1038/s44319-023-00006-4 | Pubmed:38177902

  • Lorenzo-Orts, L.#, Pauli, A. (2024). The molecular mechanisms underpinning maternal mRNA dormancy. Biochem Soc Trans 2024 Mar 13:BST20231122. doi:10.1042/BST20231122 | Pubmed:38477334

  • Chugunova, A.#, Keresztes, H., Kobylinska, R., Novatchkova, M., Lendl, T., Strobl, M., Schutzbier, M., Dürnberger, G., Imre, R., Roitinger, E., Pasierbek, P., Moreno Cencerrado, A., Brandstetter, M., Köcher, T., Agerer, B., Genger, J-W., Bergthaler, A., Pauli, A.#. (2024). Increase in ER-mitochondria contacts and mitochondrial fusion are hallmarks of mitochondrial activation during embryogenesis. bioRxiv . doi:10.1101/2024.06.11.598492v1

  • Rappol, T., Waldl, M., Chugunova, A., Hofacker, IL., Pauli, A., Vilardo, E. (2024). tRNA expression and modification landscapes, and their dynamics during zebrafish embryo development. Nucleic Acids Research (bioRxiv: 10.1101/2024.01.30.575011). doi:10.1093/nar/gkae595

2023

  • Leesch, F.#, Lorenzo-Orts, L.#, Pribitzer, C., Grishkovskaya, I., Roehsner, J., Chugunova, A., Matzinger, M., Roitinger, E., Belacic, K., Kandolf, S., Lin, TY., Mechtler, K., Meinhart, A., Haselbach, D.#, Pauli, A.# (2023). A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature. Jan;613(7945):712-720 (bioRxiv: 10.1101/2021.11.03.467131). doi:10.1038/s41586-022-05623-y | Pubmed:37615576

  • Bhat, P., Cabrera Quio, LE., Herzog, VA., Fasching, N., Pauli, A.#, Ameres, SL.# (2023). SLAMseq resolves the kinetics of maternal and zygotic gene expression during early zebrafish embryogenesis. Cell Reports. Feb 8;42(2):112070 (bioRxiv: 10.1101/2022.06.01.494399). doi:10.1016/j.celrep.2023.112070 | Pubmed:36757845

  • Gert, KRB., Panser, K., Surm, J., Steinmetz, BS., Schleiffer, A., Jovine, L., Moran, Y., Kondrashov, F., Pauli, A.* (2023). Divergent molecular signatures in fish Bouncer proteins define cross-fertilization boundaries. Nature Communications. 14, 3506 (bioRxiv: 10.1101/2022.09.01.506233). doi:10.1038/s41467-023-39317-4 | Pubmed:37316475

  • Deneke, VE.#, Blaha, A.#, Lu, Y., Draper, JM., Phan, CS., Panser, K., Schleiffer, A., Jacob, L., Humer, T., Stejskal, K., Krssakova, G., Handler, D., Kamoshita, M., Vance, TDR., Roitinger, E., Lee, JE., Ikawa, M., Pauli, A.# (2023). A conserved fertilization complex of Izumo1, Spaca6, and Tmem81 mediates sperm-egg interaction in vertebrates. bioRxiv . doi:10.1101/2023.07.27.550750

  • Ross, SE., Vázquez-Marín, J., Gert, KRB., González-Rajal, A., Dinger, ME., Pauli, A., Martínez-Morales, JR., Bogdanovic, O. (2023). Evolutionary conservation of embryonic DNA methylome remodelling in distantly related teleost species. Nucleic Acids Research. Oct 13;51(18):9658-9671 (bioRxiv: 10.1101/2023.05.24.542066). doi:10.1093/nar/gkad695 | Pubmed:37615576

2022

  • Binner, MI.#, Kogan, A.#, Panser, K., Schleiffer, A., Deneke, VE.#, Pauli, A.# (2022). The sperm protein Spaca6 is essential for fertilization in zebrafish. Frontiers in Cell and Developmental Biology. (bioRxiv: 10.1101/2021.11.19.469324). doi:10.3389/fcell.2021.806982 | Pubmed:35047514

  • Huth, M., Santini, L., Galimberti, E., Ramesmayer, J., Titz-Teixeira, F., Sehlke, R., Oberhuemer, M., Stummer, S., Herzog, V., Garmhausen, M., Romeike, M., Chugunova, A., Leesch, F., Holcik, L., Weipoltshammer, K., Lackner, A., Schoefer, C., von Haeseler, A., Bücker, C., Pauli, A., Ameres, SL., Smith, A., Beyer, A., Leeb, M. (2022). NMD is required for timely cell fate transitions by fine-tuning gene expression and regulating translation. Genes & Development. 1-20 (bioRxiv: 10.1101/2020.07.07.180133). doi:10.1101/gad.347690.120 | Pubmed:35241478

  • Kellner, MJ.#, Ross, JJ., Schnabl, J., Dekens, MPS., Matl M., Heinen, R., Grishkovskaya, I., Bauer, B., Stadlmann, J., Menéndez-Arias, L., Straw, AD., Fritsche-Polanz, R., Traugott, M., Seitz, T., Zoufaly, A., Födinger, M., Wenisch, C., Zuber, J., Vienna Covid-19 Detection Initiative (VCDI), Pauli, A.#, Brennecke, J.# (2022). A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testing. Frontiers in Molecular Biosciences. Volume 9 Article 801309 (bioRxiv: 10.1101/2020.06.23.166397). doi:10.3389/fmolb.2022.801309 | Pubmed:35433827

  • Noda, T., Blaha, A., Fujihara, Y., Gert, KR., Emori, C., Deneke, VE., Oura, S., Panser, K., Lu, Y., Berent, S., Kodani, M., Cabrera-Quio, LE., Pauli, A.#, Ikawa, M.# (2022). Sperm membrane proteins DCST1 and DCST2 are required for the sperm-egg interaction in mice and fish. Communications Biology. (bioRxiv: 10.1101/2021.04.18.440256). doi:10.1038/s42003-022-03289-w | Pubmed:35393517

  • Stock, J., Kazmar, T., Schlumm, F., Hannezo, E.#, Pauli, A.# (2022). A self-generated Toddler gradient guides mesodermal cell migration. Science Advances. Sep 16;8(37):eadd2488 (bioRxiv: 10.1101/2021.12.16.472981). doi:10.1126/sciadv.add2488 | Pubmed:36103529

  • Wu, S-HS., Lee, H., Szep-Bakonyi, R., Colozza, G., Boese, A., Gert, KR., Hallay, N., Lee, J-H., Kim, J., Zhu, Y., Pilat-Carotta, S., Hohenstein, P., Theussl, HC., Pauli, A., Koo, BK. (2022). SCON - a Short Conditional intrON for conditional knockout with one-step zygote injection. Exp Mol Med. (bioRxiv 2021: 10.1101/2021.05.09.443220). doi:10.1101/2021.05.09.443220 | Pubmed:36494589

2021

  • Gert, KR., Cabrera Quio, LE, Novatchkova, M., Guo, Y., Cairns, BR., Pauli, A.# (2021). Reciprocal zebrafish-medaka hybrids reveal maternal control of zygotic genome activation timing. bioRxiv . doi:10.1101/2021.11.03.467109

  • Guo, Y., Gert, KR., Lebedeva, S., Potok, ME., Wike, CL., Grow, EJ., Ketting, RF., Pauli, A., Cairns, BR. (2021). Maternally-inherited anti-sense piRNAs antagonize transposon expression in teleost embryos. bioRxiv . doi:10.1101/2021.11.03.467172

  • Kellner, MJ.#, Matl, M., Ross, JJ., Schnabl, J., Handler, D., Heinen, R., Schaeffer, J., Hufnagl, P., Indra, A., Dekens, MPS., Fritsche-Polanz, R., Födinger, M., Zuber, J., Vienna Covid-19 Detection Initiative (VCDI), Allerberger, F., Pauli, A.#, Brennecke, J.# (2021). Head-to-head comparison of direct-input RT-PCR and RT-LAMP against RT-qPCR on extracted RNA for rapid SARS-CoV-2 diagnostics. medRxiv . doi:2021.01.19.21250079

  • Bhat, P., Burkard, TR., Herzog, VA., Pauli, A., Ameres, SL. (2021). Systematic refinement of gene annotations by parsing mRNA 3′ end sequencing datasets. Methods in Enzymology. pages 1-19. doi:10.1016/bs.mie.2021.03.016 | Pubmed:34183122

  • Cabrera-Quio, LE., Schleiffer, A., Mechtler, K., Pauli, A.# (2021). Zebrafish Ski7 tunes RNA levels during the oocyte-to-embryo transition. PlosGenetics. 17(2): e1009390 (bioRxiv: 10.1101/2020.03.19.998716). doi:10.1371/journal.pgen.1009390 | Pubmed:33600438

  • Deneke, VE.#, Pauli, A.# (2021). The Fertilization Enigma: How Sperm and Egg Fuse. Annual Review of Cell and Developmental Biology. 37:1. doi:10.1146/annurev-cellbio-120219-021751 | Pubmed:34288709

  • Fujihara, Y.#, Herberg, S.#, Blaha, A., Panser, K., Kobayashi, K., Larasati, T., Novatchkova, M., Theussl, HC., Olszanska, O., Ikawa, M.#, Pauli, A.# (2021). The conserved fertility factor SPACA4/Bouncer has divergent modes of action in vertebrate fertilization. PNAS. 118 (39) e2108777118 (bioRxiv: 10.1101/2021.05.02.442348). doi:10.1073/pnas.2108777118 | Pubmed:34556579

  • Stock, J., Pauli, A.# (2021). Self-organized cell migration across scales – from single cell movement to tissue formation. Development. pages 1-13. doi:10.1242/dev.191767 | Pubmed:33824176

2020

2019

  • Kamieniarz-Gdula, K.#, Gdula, MR., Panser, K., Nojima, T., Monks, J., Wisniewski, JR., Riepsaame, J., Brockdorff, N., Pauli, A.#, Proudfoot, NJ.# (2019). Selective roles of vertebrate PCF11 in premature and full-length transcript termination. Molecular Cell. Apr 4;74(1):158-172.e9. doi:10.1016/j.molcel.2019.01.027 | Pubmed:30819644

2018

  • Herberg, S., Gert, KR., Schleiffer, A., Pauli, A.# (2018). The Ly6/uPAR protein Bouncer is necessary and sufficient for species-specific fertilization. Science. 361(6406), 1029–1033. doi:10.1126/science.aat7113 | Pubmed:30190407

2017

  • Rogers, KW., Lord, ND., Gagnon, JA., Pauli, A., Zimmerman, S., Aksel, DC., Reyon, D., Tsai, SQ., Joung, JK., Schier, AF. (2017). Nodal patterning without Lefty inhibitory feedback is functional but fragile. eLife. 6, e28785. doi:10.7554/eLife.28785 | Pubmed:29215332

  • Freyer, L., Hsu, CW., Nowotschin, S., Pauli, A., Ishida, J., Kuba, K., Fukamizu, A., Schier, AF., Hoodless, PA., Dickinson, ME., Hadjantonakis, AK. (2017). Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives. Cell Reports. 20, 2116–2130. doi:10.1016/j.celrep.2017.08.014 | Pubmed:28854362

  • Norris, ML., Pauli, A., Gagnon, JA., Lord, ND., Rogers, KW., Mosimann, C., Zon, LI., Schier, AF. (2017). Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. eLife. 6, e22626. doi:10.7554/eLife.22626 | Pubmed:29117894

2016

2015

2014

  • Pauli, A.#, Norris, ML., Valen, E., Chew, GL., Gagnon, JA., Zimmerman, S., Mitchell, A., Ma, J., Dubrulle, J., Reyon, D., Tsai, SQ., Joung, JK., Saghatelian, A., Schier, AF.# (2014). Toddler: an embryonic signal that promotes cell movement via Apelin receptors. Science. 343(6172):1248636. doi:10.1126/science.1248636 | Pubmed:24407481

  • Rabani, M., Raychowdhury, R., Jovanovic, M., Rooney, M., Stumpo, DJ., Pauli, A., Hacohen, N., Schier, AF., Blackshear, PJ., Friedman, N., Amit, I., Regev, A. (2014). High-resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies. Cell. 159(7):1698-710. doi:10.1016/j.cell.2014.11.015 | Pubmed:25497548

  • Zhang, Y., Vastenhouw, NL., Feng, J., Fu, K., Wang, C., Ge, Y., Pauli, A., van Hummelen, P., Schier, AF., Liu, XS. (2014). Canonical nucleosome organization at promoters forms during genome activation. Genome Research. 24(2):260-6. doi:10.1101/gr.157750.113 | Pubmed:24285721

  • Gagnon, JA., Valen, E., Thyme, SB., Huang, P., Akhmetova, L., Ahkmetova, L., Pauli, A., Montague, TG., Zimmerman, S., Richter, C., Schier, AF. (2014). Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs. PLoS One. 9(5):e98186. doi:10.1371/journal.pone.0098186 | Pubmed:24873830

2013

  • Chew, GL., Pauli, A., Rinn, JL., Regev, A., Schier, AF., Valen, E. (2013). Ribosome profiling reveals resemblance between long non-coding RNAs and 5’ leaders of coding RNAs. Development. 140(13):2828-34. doi:10.1242/dev.098343 | Pubmed:23698349

2012

  • Pauli, A.#, Valen, E., Lin, MF., Garber, M., Vastenhouw, NL., Levin, JZ., Fan, L., Sandelin, A., Rinn, JL., Regev, A., Schier, AF#. (2012). Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis. Genome Research. 22(3):577-91. doi:10.1101/gr.133009.111 | Pubmed:22110045

2011

  • Pauli, A.#, Rinn, JL., Schier, AF#. (2011). Non-coding RNAs as regulators of embryogenesis. Nature Review Genetics. 12(2):136-49. doi:10.1038/nrg2904 | Pubmed:21245830

  • Strübbe, G., Popp, C., Schmidt, A., Pauli, A., Ringrose, L., Beisel, C., Paro, R. (2011). Polycomb purification by in vivo biotinylation tagging reveals cohesin and Trithorax group proteins as interaction partners. PNAS. 108(14):5572-7. doi:10.1073/pnas.1007916108 | Pubmed:21415365

2010

  • Pauli, A.#, van Bemmel, JG., Oliveira, RA., Itoh, T., Shirahige, K., van Steensel, B., Nasmyth, K#. (2010). A direct role for cohesin in gene regulation and ecdysone response in Drosophila salivary glands. Curr Biol. 20(20):1787-98. doi:10.1016/j.cub.2010.09.006 | Pubmed:20933422

  • Oliveira, RA., Hamilton, RS., Pauli, A., Davis, I., Nasmyth, K. (2010). Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei. Nature Cell Biol. 12(2):185-92. doi:10.1038/ncb2018 | Pubmed:20081838

2008

  • Pauli, A., Althoff, F., Oliveira, RA., Heidmann, S., Schuldiner, O., Lehner, CF., Dickson, BJ., Nasmyth, K. (2008). Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons. Dev Cell. 14(2):239-51. doi:10.1016/j.devcel.2007.12.009 | Pubmed:18267092

2006

  • Panse, VG., Kressler, D., Pauli, A., Petfalski, E., Gnädig, M., Tollervey, D., Hurt, E. (2006). Formation and nuclear export of preribosomes are functionally linked to the small-ubiquitin-related modifier pathway. Traffic. 7(10):1311-21. doi:10.1111/j.1600-0854.2006.00471.x | Pubmed:16978391

2004