Welcome to our new students Theresa, Anna and Sara!
01 Oct 2020
Theresa is a PhD student, Anna and Sara joined as interns. All three will work on different aspects of fertilization. Welcome!
Theresa is a PhD student, Anna and Sara joined as interns. All three will work on different aspects of fertilization. Welcome!
When institutes had to shut-down during the pandemic mid of March, many scientists across the VBC campus joined forces to help to fight the virus. Over the past five months, Julius Brennecke (IMBA) and Andi (IMP) worked together with a team of three PhD students, Max Kellner (PhD student at the LMB), Jakob Schnabl and Julian Ross (PhD students at IMBA), to develop a rapid, highly sensitive and inexpensive isothermal SARS-CoV-2 test. The final push was geared towards making the reaction open-access: any molecular biology lab in the world can now produce the enzymes required for the reaction. This is a major step forward towards making testing possible at population-scale and accessible also to low-resource countries.
This work would not have been possible without the help of our on-site biochemists Irina, Benedikt and Johannes and the continous support from our institutes and labs.
Check out our preprint on bioRxiv: “A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testing.”
The preprint can be found here.
A somewhat belated welcome to our interns Mirjam, Lena and Lorena! Mirjam is working with Victoria and already fully hooked on fertilization and microscopy. Lena has been introduced by Anastasia into the complicated life of mitochondria, the powerhouse of the cell. And Lorena has most recently joined Krista to work on fertilization, or rather on what happens if two species that should not mate mate. It’s great to have you all around!
Congratulations to Victoria who was awared a prestigious HFSP (Human Frontier Science Program) postdoctoral fellowship. Victoria was selected as one of the 50 recipients world-wide out of the pool of 544 applications, and plans to study the molecular basis of gamete binding and fusion in zebrafish. Big congratulations Victoria!
A press release for the 2020 HFSP postdoc fellowships can be found here.
Delighted that my lab will join forces with Verena Ruprecht (coordinator) at the CRG in Barcelona, Spain, and Liu Yan-Jun at Fudan University, Shanghai, China, in a HFSP Young Investigator Grant to study biophysical aspects of fertilization. Our project is one of eight Young Investigator Grants chosen for funding in the latest call of the Human Frontier Science Program (HFSP). Having been awarded this grant means that I/my lab have benefited from continous funding from the HFSP since 2010 (postdoc fellowship, Career Development Award, Young Investigator Grant), and we are extremely grateful for this continous support of our research. Thank you HFSP!
More information on the Young Investigator Grant can be found here:
Check out the latest preprint from the Pauli lab on bioRxiv: “Zebrafish Ski7 tunes RNA levels during the oocyte-to-embryo transition.” Congratulations to the first author Quio!
The preprint can be found here.
The Pauli lab’s first virtual lab meeting is in the books! With everyone working from home due campus-/Vienna-/Austria-wide social isolation measures in light of Covid-19, this turned out a successful experiment. Thanks to Victoria for being our guinea-pig in giving it, and to everyone for ‘zooming in’ and actively contributing!
Congratulations to Andreas who was awared a BIF (Boehringer Ingelheim Fonds) PhD fellowship for his graduate studies in the Pauli lab! Wonderful news, and congrats on becoming part of the BIF community!
Fantastic news from the Fred Hutchinson Cancer Research Center in Seattle: Victoria was awarded the prestigious international Harold M. Weintraub Graduate Student Award for her “outstanding achievements during graduate studies” in Stefano Di Talia’s lab at Duke University. Victoria will attend a symposium of Weintraub Award winners in May at the Fred Hutchinson Cancer Research Center to share her doctoral work. Big congratulations for this well-deserved award!
More information on the award and Victoria’s graduate student work can be found here:
Many members of the Pauli lab took part in the 3rd regional DevStem meeting, this year hosted by the IST. A wonderful day of top-notch science presented by the leaders of tomorrow (= PhD students and postdocs from institutes and universities in the Vienna area). AND a fantastic talk by Jessica from our own lab on Toddler signaling during gastrulation!
Last week brought double success for the Pauli lab: With Anastasia Chugunova and Laura Lorenzo Orts not only one but two postdocs received the fantastic news from the European Commission that their Marie Curie postdoctoral fellowship applications had been successful! Big congratulations to both of you! You can read more about it here.
What are the mechanisms that match a specific species’s sperm to the same species’s egg? If you are curious about knowing more about this fascinating topic, check out Krista’s review on ‘Species-specific mechanisms during fertilization’.
Who would have thought that a PhD student from the Pauli lab would be awarded a ‘Perutz Crystal Award’ for her excellent research in structural biology? Big congratulations to Frieda, who suprised quite a few members of the VBC structural community about her structural studies during zebrafish development. This is a first for the Pauli lab, and only possible due to a fantastic collaboration with David Haselbach and his lab, as well as Laura in our own lab. Congratulations to Frieda and the whole team!
Happy New Year from all of us in the Pauli lab! It’s been an exciting, fun and successful 2019, which saw the first Pauli lab PhD student (Sarah) graduate and a new PhD student (Andreas) as well as three postdocs (Anastasia, Laura, Victoria) join. We are curious to see what 2020 will bring along!
Congratulations to Victoria Deneke whose picture of a regenerating zebrafish tail-fin was selected for the 2020 MBL (Marine Biological Laboratory) calendar! Victoria took this picture as a student of the MBL zebrafish course this summer in Woods Hole as part of a class on fin regeneration by Ken Poss. To see all pictures that were selected for the MBL calendar, check out the website. You can order the 2020 calendar here.
Congratulations to Karin Panser who won the 3rd prize in the international scientific image contest by Huygens for her stunning confocal image of somites of a 2-day old zebrafish larva. Actin (phalloidin) in orange, nuclei (DAPI) in blue. To read more about the prize and to see all winning pictures, check out the website.
We are happy to join a diverse group of RNA biologists across Austria (from Vienna, Innsbruck and Klosterneuburg) as part of the newly funded SFB grant RNA-DECO. Congratulations to everyone who contributed to the success of this team-effort!
Congratulations to Laura for having been awarded a prestigious EMBO long-term postdoctoral fellowship. Big congratulations for this well-deserved award!
Before the year is over it’s a good time to say a big THANK YOU to everyone - it’s great to see how our lab has grown together (apart from having literally grown…) over the past months. Keep up the great work, team-spirit and motivation, and let’s see what 2020 will bring for us!
LOTS of sperm, eggs, ribosomes, an exosome, mitochondria, fish, flies (and a ginger bread house as well)… Not the usual type of cookies you would think of for gingerbread baking, but lots of fun and amazingly creative designs! Great team-work in coming up with a ‘special cookie’ for every lab member - way to go, Pauli lab, this was lots of fun!
At this year’s PhD symposium prize giving the Pauli lab had not only one but two reasons to celebrate: Congratulations to Sarah Herberg, the Pauli lab’s very first PhD student graduate, for winning a VBC PhD student award for her PhD thesis, and to Krista Gert for winning the poster prize of the symposium! Well done and congratulations to the ‘2018 Bouncer-team’!
This year’s VBC PhD Symposium ReConnect marked the 25th anniversary of the Vienna Biocenter PhD program. Alumni from all years had been invited back to the campus to join current PhD students to celebrate this special occasion. The diverse program included scientific talks by alumni, career workshops by alumni for current students, a reception at the Viennese city hall and a special ‘25 year VBC PhD program’ tram, a VBC QuizShow, graduation ceremony and the VBC PhD student band ‘the pellets’ at the final party. ReConnect was a great success!
Congratulations to Anastasia, who successfully defended her PhD thesis back in Moscow, Russia. Now it’s finally also officially Dr. Chugunova!
Laura, who did her PhD in Michael Hothorn’s lab in Geneva, Switzerland, was awarded a postdoctoral fellowship from the SNF (Swiss National Science Foundation). Big congratulations for this well-deserved award!
Anastasia was awarded a VIP2 postdoctoral fellowship, a newly launched international fellowship program at the Vienna Biocenter co-funded by the European Union’s 2020 Horizon research and innovation programme. Big congratulations for this well-deserved award!
Krista was awarded a DOC fellowship from the Austrian Academy of Sciences (OEAW) for her PhD studies in the Pauli lab. Krista is interested in investigating the role of Bouncer in species-specific fertilization. Big congratulations to this well-deserved award!
For this year’s lab retreat the Pauli Lab headed to the Mariazeller mountains in Styria, Austria. Thanks to the contributions of everyone, we had a great mix of science, sozializing and activities, including a visit to the famous Pirker Lebkuchen manufacturer, hiking through Austria’s ‘Gran Canyon’ (Naturpark Vorderötscher) and to the summit of the Gemeindealpe before heading down the moutain in ‘mountaincarts’. The question ‘when will we have our next lab retreat?’ when heading back to Vienna shows that this retreat was a success. What a fun three days with stimulating discussions and great company!
Big congratulations to Victoria for being amongst the ‘honorable mentions’ for the 1st International Max Birnstiel award, a prize awarded annually to outstanding doctoral students for their PhD research conducted outside of Austria. Victoria receives this honor for her PhD work in Stefano Di Talia’s lab at Duke University, USA. Fantastic start at the first day as a postdoc in our lab!
More information about this year’s awardees can be found here.
Welcome to our new postdoc, Victoria Deneke! Victoria obtained her PhD in Stefano Di Talia’s lab at Duke University, USA, where she studied cell cycle synchronization in Drosophila development. In the Pauli lab, Victoria will join the fertilization crew to investigate mechanisms of gamete binding and fusion. Welcome on board!
Welcome to our new postdoc, Laura Lorenzo Orts! Laura obtained her PhD in Michael Hothorn’s lab at the University of Geneva where she worked at the interphase of plant biology, translational regulation and structural biology. In the Pauli lab, Laura will join the translational team to investigate the secretes of translational regulation during embryogenesis. Welcome on board!
Over the past two months we had James Kiraly from the University of Texas at Austin, US, joining our lab as a VBC summer student. This year marked the 10th anniversary of the VBC summer school, which we celebrated with a symposium where alumni and current students presented their research. It was a great opportunity to catch up with former summer students (Tiago Alves from Brazil, VBC summer student in the Pauli lab in 2017), and inspiring to see 1) what students can achieve within 2 months of summer school, and 2) what former VBC summer school students have been up to in the meanwhile (anything from being postdocs/PhD students at Stanford, Caltec, MIT and the VBC to working at NASA etc.). Keep up your passion for science and the great work!
If you are a scientist and have been to the Marine Biological Labs in Woods Hole in summer, you will always want to come back to this buzzing environment full of eminent scientists and positive vibe :) This year was a first for the Pauli lab to take part in the zebrafish course in three different roles: as ‘student’ (future postdoc Victoria Deneke), as ‘TA’ (current PhD student Jessica Stock), and as faculty (Andi). Irrespective of our role, we had a fantastic time!
The Pauli lab was well represented at meetings which reflect the breadth of topics that we are interested (in a wider sense…) in the Pauli lab:
I think it’s safe to say that we have learnt a lot, got new ideas, had many fruitful discussions and expanded our scientific network (and met old friends on the way!).
Bouncer made it into F1000prime! “…This wonderful research indicates that studies in model organisms, even on species-unique genes, continue to provide paradigms that can be used to guide work in more complex mammalian systems.” You can read the full recommendation from Hila Toledano here.
Welcome to James, who will join us as a VBC summer student for the next two months to figure out everything we don’t yet understand about translation in the early embryo (well, quite some work waiting for you, James ;-)!)! Welcome on board of the Pauli lab!
Welcome to our new PhD student Andreas, our newest addition to the team! We are very happy to welcome you on board of the Pauli lab!
Time to say good-bye to Sarah, and welcome to Anastasia! Sarah, we wish you all the best for your future endavors, wherever it will take you.
It’s been a very special day for the Pauli lab: Very proud of Sarah, the very first PhD graduate from the Pauli lab. Big congratulations, Dr. Herberg! It’s been an extremely productive and successful 3.5 years discovering Bouncer’s function in fertilization. While you will leave us soon, your initial findings have opened up new projects in the lab that will surely keep other students/postdocs busy for the next few years…
Welcome to Anastasia, the newest member of our team! Anastasia did her PhD at Lomonosov Moscow State University and Skolkovo Institute of Science and Technology in the laboratories of Prof. Petr Sergiev and Prof. Olga Dontsova. Welcome on board of the Pauli lab!
We are very proud to have contributed to uncovering the function and mechanism of the transcription termination factor PCF11 in vertebrates. This has been a highly successful collaboration led by Kinga Kamieniarz-Gdula in Nick Proudfoot’s lab at Dunn School, Oxford University. Congratulations to all authors, particularly to Karin Panser from our lab who performed the zebrafish experiments!
Congratulations to Friederike, who successfully defended her PhD thesis that she worked on in Alipasha Vaziri’s lab. Now it’s officially Dr. Schlumm!
Time to say good-bye to Tomas and Lisa - you will be missed from the toddler team! We wish you all the best for your new adventures!
Benni, who has already worked in the lab as an internship student, will stay with us and continue his research as a Master student. Great decision, Benni!
Happy New Year from all of us in the Pauli lab! It’s been an exciting, fun and successful 2018 - am curious to see what 2019 will bring along!
The Pauli lab demonstrated some great teamwork and riddle-solving capabilities at an escape room. Every team managed to find the hidden clues to escape from their room (though the prisoners made it extra thrilling with only 2 seconds left…) and had lots of fun on the way!
Andi is one of 26 researchers selected to become an EMBO Young Investigator. For the next three years, Andi and her lab will benefit from the great EMBO YIP community and possibilities to network with other young and well-established scientists.
Two success stories from the Pauli lab:
Congratulations to Sarah Herberg for winning the Mattias Lauwers Award 2018! Sarah was nominated by her fellow VBC students for the best Monday seminar presentation of the year.
Congratulations to Quio (Luis Enrique Cabrera Quio) for winning the first ever Science Slam at the VBC PhD Symposium 2018! Among all of the great and creative contributions, Quio’s dancing performance, “RNA Degradation: The Musical,” sung by Krista Gert thrilled the audience and showed off amazing, hidden talents!
Big congratulations to Sarah, Quio & Krista!
For this year’s VBC PhD Symposium, an entirely student-led event, students chose the theme, “Metamorphosis: Transforming Science.” The event brought scientists from various disciplines together, ranging from technology and communication, to health and the environment. It was a big success! It also featured the very first (of hopefully many) installation of Science Slam. Jessica Stock was one of the co-organizers of this event, and designed the very creative and beautiful poster.
Great job to all of the organizers for such a successful symposium!
The first Pauli lab paper is out in Science! We report the discovery of a short protein that acts as the gatekeeper of the oocyte (hence the name “Bouncer”). Bouncer is essential for fertilization in zebrafish, and, most remarkably, expressing a different species’ Bouncer on zebrafish eggs allows the other species’ sperm to enter. Big congratulations to the authors Sarah Herberg, Krista Gert, and Alex Schleiffer (IMP/IMBA).
Full story and more pictures can be found here.
Over the past five weeks, students of the Pauli lab joined Andi for conducting research projects in Woods Hole, MA, USA. The stimulating environment with plenty of interesting talks and scientific discussions, the openness of everyone and willingness to share and interact, and the amazing range of animals we could get our hands on (from sea urchins to sea stars, iconic horseshoe crabs, cephalopods, and, of course, different species of fish) made our stay a big success. We were sad to leave Woods Hole, but are also looking forward to our home base at the IMP to put some of our new ideas into action!
Time to celebrate: The first paper from the Pauli lab got accepted! Very proud of the two PhD students Sarah Herberg and Krista Briedis (soon to be Gert), and Alex Schleiffer from the IMP who helped with the phylogenetic analyses. #Bouncer #proudPI #happyStudents
Andi is one of the 28 international scientists who has been awarded the 2018 Whitman Center Fellowship to conduct research at the Marine Biological Laboratory (MBL) in Woods Hole, Massachusetts, USA. This fantastic opportunity will also enable students of the Pauli lab to come along to work on their own projects and broaden their horizons at this iconic place.
The Vienna BioCenter (VBC) opened its doors to the public to highlight some of the research conducted at the IMP, IMBA, GMI and MFPL. Members of the Pauli lab participated with a hands-on station where anyone could observe little zebrafish embryos develop, and watch their beating hearts. It’s been really rewarding to spark the interest in science of so many people from young to old.
Welcome to Friederike, a former PhD student in Alipasha Vaziri’s lab at the IMP!
Welcome to Lisa, the newest addition to the Pauli lab crew. Lisa has joined us as a Master student - welcome on board!
The Pauli lab was treated to an in-depth tour of the Haus des Meeres given by the deputy director and curator, Daniel Abed-Navandi. He taught us a lot about the different species on display, and gave us a behind-the-scenes look of how the aquarium operates. Some of the cool organisms we were able to see included a poisonous cone snail species, lots of little jellyfish, and the aquarium’s thriving seahorse population.
Once upon a time at the IMP…
On the 12th of January, the Pauli lab turned the IMP into a whole new world when holding their Disney-themed beer hour. With princesses on cupcakes and a magical potion from Merlin’s cauldron, everyone gathered for the evening and enjoyed the bare necessities of life. Hakuna matata!
Despite adverse weather conditions everyone who made it to the Ice-Skating ring for the IMP & IMBA Xmas party had a great time. Merry Christmas and Happy Holidays from the Pauli lab!
Wednesday night saw model organisms gone loose in the Museum of Natural History in Vienna. The Pauli and Obenauf labs teamed up for a Xmas Scavenger Hunt as Drosophila melanogaster, Mus musculus, Ambystoma mexicanum and Danio rerio to take a picture with the scariest animal, rebuild the IMP logo and much more. Thanks to Manuela Steurer for the great questions that made this such a memorable and fun event!
Students from the HBLVA Rosensteingasse were visiting us today to get a glimpse of working at an international research institute, and of course to see our zebrafish! There were lots of questions and interesting discussions - thanks Karin for helping answer them all! We had a great time showing our visitors around, and it seemed that they enjoyed the ‘lab-outing’, too!
It’s Gansl-season (goose-season) in Austria. The Pauli lab did not miss out and enjoyed a typical Gansl dinner at Rudi’s Beisel. So many geese!
The Pauli lab is growing.
Welcome to our three new students: Krista and Frieda, our new PhD students; and Xue, who will be a shared Master student with the Cochella lab.
We don’t need a reason to meet up for a lab-dinner, but this time there were in fact three!
Welcome to Lisa who came ‘all the way from Krems University’ for joining us for an internship!
The Pauli Lab headed to Gustav’s Castle at the Rax for three days of fun and science. Who would have thought that each one of us would climb up a 20m high pole (and jump down), and hike up the Predigtstuhl? Great team-play!
July was conference time!
Lots of food for thought and interesting discussions, and great to meet new people and catch up with old friends and colleagues!
Welcome to Tiago, who came all the way from Brazil to join us as a VBC (Vienna BioCenter) Summer Student! Tiago = expert in jumping photos :)
Karin and Andi were members of the successful IMPerfectos, the already legendary IMP Dragon Boating team. This year, the IMPerfectos managed to put everything on the line and managed to bring the title back to the IMP by a photo-finish! Big congrats to the whole team!
Congratulations to Krista for successfully defending her master’s thesis at her “home” university (Linköping University) in Sweden!
Members of the Pauli lab joined in with colleagues from the Vienna Biocenter (IMP, IMBA, GMI, MFPL) to March for Science in Vienna.
While we have already been happily working here for a few months, today was the official opening ceremony of the new IMP building with high-profile guests including scientist Emmanuelle Charpentier and Austrian president Hugo van der Bellen! Big thank you to Boehringer Ingelheim for the investment into hopefully many more years of exciting science at the IMP!
Welcome to Krista, the very first master student in the Pauli lab!
The Pauli and Obenauf Labs joined forces in “Eisstock-Schiessen” at the Danube Canal in Vienna before heading to a well-deserved Christmas dinner.
Congratulations to Quio for being awarded the Boehringer Ingelheim PhD fellowship!
The whole IMP is moving just around the corner (or in fact ‘across the bridge’) to our new home, the brand-new IMP building! Fantastic effort by everyone involved in the planning, organization and execution of the logistic master-piece.
A note on the side: The Pauli lab has the largest number of ‘members’ in the new building - our ~5000 fish arrived happily in their new facility on the top floor!
Welcome to the Pauli Lab, Jessica!
Congratulations to Sarah for winning a DOC fellowship from the Austrian Academy of Science (OEAW)!
The Pauli lab’s first manuscript is online: “Decoding sORF translation – from small proteins to gene regulation”! Congratulations, Quio and Sarah!
Fully in line with the Pauli lab motto: combine science & fun.
Welcome to Krista, who will join us for two months as a summer student!
The Pauli lab joins the whole IMP+IMBA for the already legendary yearly skiing-trip. This year we went to Villach for some awesome skiing, snowboarding and sledging! Well done to Sarah and Quio for their first ever snow-boarding/skiing!
Sarah and Quio get to know the ins and outs of being a PhD student at the VBC (Vienna Biocenter).
A good start into the new year with the first edition of a Pauli lab dinner at Andi’s place!
1 + 1 = 2! Welcome to Quio, the second PhD student of the Pauli lab!
The Pauli lab joined CP Heisenberg’s lab for a fun+science lab retreat near Renz, close to the Czech border.
Welcome to the Pauli lab’s very first PhD student Sarah!
Our first fish are here and happily swimming around in their shiny tanks in our brand-new fish facility! With this, IMP got about 3000 new (mostly still underage) members!
A former microscope room at the IMP is converted into a state-of-the-art fish facility. Amazing what one can build within a month! Thanks to Tecniplast and everyone from the IMP who helped together to make this happen!
Andi arrives in Vienna, and with the first lab member Karin being already on board, the Pauli lab is officially alive! Let the fun start!
Karin visits Andi in Boston to learn the ins-and-outs of zebrafish from the master of the Schier lab fish facility, Steve Zimmerman!