Lab News

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SPACA4 paper published in PNAS

24 Sep 2021

It’s been a while in the making, and it’s great to see it finally out in PNAS! In collaboration with Yoshitaka Fujihara and Masahito Ikawa’s lab, we discovered an interesting evolutionary twist in vertebrate fertilization: While we previously identified egg-expressed Bouncer in fish as essential for sperm-egg membrane interaction (Herberg et al., 2018), we report here that its mammalian homolog SPACA4 is expressed in sperm and necessary for zona pellucida penetration. Hence, Bouncer and SPACA4 present a fascinating example of homologous proteins that have evolved different mode of actions to ensure efficient fertilization in vertebrates. Congratulations to all authors, in particular Sarah who started the project, and Andreas and Karin from the Pauli lab as well as Yoshi from the Ikawa lab who took it over and finalized the research!

Link to the

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All the best to Eduardo

31 Aug 2021

This week we also said goodbye to Eduardo, a Salvadoran undergraduate student who worked with Victoria this summer. Eduardo was the first student to take part in our initiative to provide a world-class research experience to a talented student from a developing country. We are extremely proud of the work he did in our lab and wish him the very best on his return to El Salvador! We are looking forward to keep providing a space for talented aspiring scientists to grow and flourish. Thank you, Eduardo!

For more information on Eduardo’s stay and on the Austria-El Salvador initiative, check out this news post.

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Goodbye to our VBC summer student Mireia

30 Aug 2021

The summer is coming to an end and unfortunately we have to say goodbye to our VBC summer student Mireia Codina. Over the last two months Mireia worked with Jessica on investigating how Toddler regulates mesodermal cell migration. During the final symposium of the VBC summer school Mireia gave an excellent talk and was one of three speakers to be awarded for her work and presentation.

It was such a pleasure to have Mireia in the lab, and the Toddler team will miss her dearly!

For more information on the Vienna BioCenter Summer School, check out this website.

Find older news in the news archive.